Prospective cross-sectional study reveals menstruation may not trigger FMF attacks in adolescents, suggesting symptoms could indicate premenstrual discomfort.
Our findings raise the possibility that menstruation does not uniformly act as a trigger for FMF attacks and that a subset of symptoms reported during the menstrual period may reflect premenstrual discomfort or PMS/PMDD-like features rather than true FMF attacks.
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Kaya et al. (2026) studied this question.
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