Sustained Clinical Improvement in Psoriasis Assessed by Psoriasis Area Severity Index (Pasi) Score Following Ayurvedic Treatment: A Case Series

Psoriasis is a chronic immune-mediated skin disorder with recurrent episodes, significant comorbidities, and impaired quality of life. Limitations of conventional therapies and fear of recurrence highlight the need for safe and sustainable alternatives. Present case series aims to evaluate the clinical outcomes of an Ayurveda-based structured therapeutic protocol in patients with chronic psoriasis. This case series included nine patients diagnosed with psoriasis based on clinical examination and Psoriasis Area Severity Index (PASI) scoring. A structured, phased Ayurvedic treatment protocol using a core group of herbal formulations was administered with individualized modifications. Patients were followed for 7–24 months. Clinical outcomes were assessed using changes in PASI scores and symptom improvement. All patients demonstrated substantial reduction in PASI scores, with improvement ranging from approximately 70% to 100%. Most patients showed marked or good clinical improvement, with reduction in itching, scaling, and associated symptoms. Sustained benefits were observed in the majority of cases, with minimal recurrence and no reported adverse effects. The findings suggest that present structured Ayurvedic therapeutic protocol may offer effective and sustained clinical improvement in psoriasis. Further randomized controlled trials with standardized outcome measures are warranted to validate these results.