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April 6, 2026Military Medicine0 citations

Equipping Austere Surgical Teams for Coagulopathy Management

The Second Battle: Equipping Austere Surgical Teams for Post-Resuscitation Coagulopathy

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Authors

JCJonathan L CusterPBPatrick J Bedard

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Overview

This commentary advocates for fibrinogen concentrate use in austere surgical teams, enhancing coagulopathy care in combat settings.

Key Points

  • The aim is to demonstrate the need for fibrinogen concentrate in managing coagulopathy during prolonged casualty care.
  • Analysis of current military and civilian transfusion practices
  • Review of existing literature, including the FIBRES trial and systemic reviews
  • Examination of logistical benefits of fibrinogen concentrate over cryoprecipitate
  • Fibrinogen concentrate is clinically non-inferior to cryoprecipitate for treating hypofibrinogenemia.
  • FDA approved fibrinogen concentrate for acquired fibrinogen deficiency eliminates regulatory barriers.
  • Majority of combat casualties exceed volume thresholds warranting fibrinogen supplementation.

Cite This Study

Custer et al. (2026) studied this question.

synapsesocial.com/papers/69d34e739c07852e0af98155https://doi.org/10.1093/milmed/usag144
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