Cimigenoside enhances Taxol chemosensitivity in triple‐negative breast cancer via the γ‐secretase/RBPJ‐PXR axis

Key Points

• The study aims to investigate the effect of cimigenoside on Taxol sensitivity in triple-negative breast cancer through specific molecular pathways.
• In vitro experiments assessing the effects of cimigenoside on TNBC cells.
• Evaluation of the γ-secretase/RBPJ-PXR axis.
• Measurement of chemosensitivity through cell viability assays.
• Cimigenoside significantly increases Taxol sensitivity in TNBC cells.
• Activation of the γ-secretase/RBPJ-PXR axis is implicated in the enhanced sensitivity.
• Improvements in cell viability suggest potential for therapeutic applications.