Why the study?
Does the addition of atrial fibrillation ablation to mitral-valve surgery improve freedom from atrial fibrillation at 1 year in patients with persistent or long-standing persistent atrial fibrillation?
Does the addition of atrial fibrillation ablation to mitral-valve surgery improve freedom from atrial fibrillation at 1 year in patients with persistent or long-standing persistent atrial fibrillation?
Adding surgical atrial fibrillation ablation during mitral valve surgery improves 1-year freedom from AF but increases the need for permanent pacemakers.
Pacemaker risk warrants caution with ablation during mitral-valve surgery; confirms 1-year AF freedom benefit in RCT.
The addition of atrial fibrillation ablation to mitral-valve surgery significantly increased the rate of freedom from atrial fibrillation at 1 year among patients with persistent or long-standing persistent atrial fibrillation, but the risk of implantation of a permanent pacemaker was also increased. (Funded by the National Institutes of Health and the Canadian Institutes of Health Research; ClinicalTrials.gov number, NCT00903370.).
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Gillinov et al. (2015) studied this question.
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