Severe Generalized Disease (Encephalohepatomyocarditis) Occurring in the Newborn Period and Due to Infection With Coxsackie Virus, Group B

2 fatal cases of generalized infection in the neonatal period with Coxsackie virus, Group B, Type 4, alongside a review of 25 cases of this disorder. The study also included newborn mice inoculated with the virus strains.

Clinical and pathologic features, including viral presence in myocardial, spinal cord, and liver tissues, and pathologic effects (destruction of anterior horns of the spinal cord) in inoculated newborn mice.