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April 1, 2020Sohag Medical Journal

Prognostic value of serum lactate during anesthesia for cardiac surgery.

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Why the study?

Cardiopulmonary bypass affects tissue perfusion during cardiac surgery, and blood lactate in relation to patient morbidity serves as an indicator of its reliability as a perfusion marker.

Does serum lactate measurement during and after cardiac surgery predict ICU length of stay in patients undergoing cardiac surgery?

Population

66 patients admitted for cardiac surgery

Comparison

Serial blood lactate measurements across perioperative and ICU time points

Design

Prospective observational study

Follow-up

48 hours of staying ICU

Authors

MMMarwa Ahmad MahrousSohag UniversityKHKhaled HassanMansoura UniversityAAAbdelrahman AbdelrahmanSohag University

Discussion

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Implication

Lactate levels were associated with ICU stay after cardiac surgery; leaves open whether lactate-guided care improves outcomes.

Structured PICO

Does serum lactate measurement during and after cardiac surgery predict ICU length of stay in patients undergoing cardiac surgery?

P
Population
n=66 patients admitted for cardiac surgery at Sohag university hospital and Sohag Heart Institute between October 2017 and April 2019.
I
Intervention
Measurement of serum lactate levels via arterial blood gas at induction, before cardiopulmonary bypass (CPB) weaning, after 24 hours in ICU, and after 48 hours in ICU.
O
Outcome
ICU length of stay (less than 48 hours vs more than 48 hours)

Serum lactate levels measured during and after cardiac surgery correlate significantly with ICU length of stay.

Cite This Study

Mahrous et al. (2020) studied this question.

synapsesocial.com/papers/69d422acc696f5663a792d9ehttps://doi.org/10.21608/smj.2020.21163.1085
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Studies on the Peripheral Circulation and Metabolism in Man I. Oxygen utilization and lactate‐pyruvate formation in the legs at rest and during exercise in healthy subjects1961 · 50 citations
  2. 2Objective Index of Haemodynamic Status for Quantitation of Severity and Prognosis of Shock Complicating Myocardial Infarction1968 · 32 citations
  3. 3Experimental and Clinical Studies on Lactate and Pyruvate as Indicators of the Severity of Acute Circulatory Failure (Shock)1970 · 715 citations
  4. 4'Lactate washout' following circulatory arrest1988 · 22 citations
  5. 5Oxygen debt, lactate, pyruvate, and excess lactate after muscular work1962 · 73 citations