Why the study?
The QRS-T angle is a prognostic marker across clinical settings, but the impact of TAVI on it has not been investigated.
Does transcatheter aortic valve implantation (TAVI) alter the frontal QRS-T angle in patients with severe aortic stenosis?
Does transcatheter aortic valve implantation (TAVI) alter the frontal QRS-T angle in patients with severe aortic stenosis?
TAVI induces an early, transient widening of the QRS-T angle followed by a significant narrowing at 30 days, likely reflecting initial ischemic stress and subsequent normalization of left ventricular hemodynamics.
Transient QRS-T widening post-TAVI should not yet change practice; hypothesis-generating for its role in assessing LV recovery.
Objective: This study aimed to investigate changes in the frontal QRST angle in patients who underwent transcatheter aortic valve implantation (TAVI).Background: The QRS-T angle is a prognostic marker in several clinical settings.The impact of TAVI on the QRS-T angle, especially in the long term, has not been investigated thus far.Methods: A total of 104 patients undergoing transcatheter aortic valve replacement due to severe aortic stenosis underwent a standardized digital 12-lead ECG for the calculation of the QRS-T angle before and 24 h after the intervention, as well as 30 days after the intervention.Results: There was a significant and dynamic change in the QRS-T angle during the TAVI procedure.An initial increase in the number of patients with a wider QRS-T angle (>90) was notable immediately after valve replacement.After 30 days, there was a significant decrease in the number of patients with a wide QRS T-angle. Conclusion:The QRS-T angle widens early after transcatheter aortic valve replacement and improves below the baseline during a 3 months follow-up.This could be related to the cardiac ischemic stress during valve intervention.In contrast, QRS-T angle narrowing during follow-up might reflect the normalization of left ventricular hemodynamics and prognostic improvement.
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Amirie et al. (2026) studied this question.
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