Why the study?
Does ramipril retard the development of aortic valve stenosis in a rabbit model?
Population
rabbit model
Design
Preclinical
Authors
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Offers preclinical support for ramipril in AVS; leaves open clinical translation pending human trials.
Does ramipril retard the development of aortic valve stenosis in a rabbit model?
In a rabbit model, ramipril retards the development of aortic valve stenosis and limits endothelial dysfunction, providing a rationale for future human studies.
Ngo et al. (2010) studied this question.
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