What question did this study set out to answer?

To evaluate hemodynamic changes in patients with cardiac tamponade following pericardiocentesis.

August 1, 1978CirculationOpen Access

Cardiac tamponade: hemodynamic observations in man.

View Full Paper

Ask AI

Bookmark

Why the study?

Does pericardiocentesis improve hemodynamic parameters in patients with pericardial effusion and cardiac tamponade, and what determines the presence of pulsus paradoxus?

Population

19 patients with pericardial effusion, including 14 with cardiac tamponade and 5 without cardiac tamponade.

Comparison

Pericardiocentesis (with gradual fluid withdrawal) vs Pre-pericardiocentesis baseline and patients…

Design

Cohort

Follow-up

Immediate (peri-procedural)

Authors

PRP S ReddyTufts University ECE I CurtissCurtiss-Wright (United Kingdom)JOJ D O'TooleSt. George's University

Discussion

Member takes

Implication

Supports hemodynamic benefit of pericardiocentesis in tamponade; leaves open pulsus paradoxus determinants in observational data.

Key Points

To evaluate hemodynamic changes in patients with cardiac tamponade following pericardiocentesis.
Conducted hemodynamic studies in 19 patients with pericardial effusion before and after pericardiocentesis.
Monitored right atrial pressure, cardiac output, and pulmonary arterial wedge pressure.
Assessed the presence of pulsus paradoxus along with ventricular filling pressures.
In patients with cardiac tamponade, right atrial pressure decreased from 16 +/- 4 mm Hg to 7 +/- 5 mm Hg, P < 0.001.
Cardiac output increased significantly from 3.87 +/- 1.77 l/min to 7 +/- 2.2 l/min following intervention.
Pulmonary arterial wedge pressure decreased significantly in patients with tamponade post-pericardiocentesis, P < 0.001.

Structured PICO

Does pericardiocentesis improve hemodynamic parameters in patients with pericardial effusion and cardiac tamponade, and what determines the presence of pulsus paradoxus?

Population

19 patients with pericardial effusion, including 14 with cardiac tamponade (10 with pulsus paradoxus, 4 without pulsus paradoxus who had chronic renal failure) and 5 without cardiac tamponade.

Intervention

Pericardiocentesis (with gradual fluid withdrawal)

Comparator

Pre-pericardiocentesis baseline (before-and-after comparison) and patients without cardiac tamponade

Outcome

Changes in hemodynamic parameters (right atrial pressure, cardiac output, inspiratory systemic arterial pulse pressure, right ventricular end-diastolic pressure, and pulmonary arterial wedge pressure)surrogate

Pericardiocentesis significantly improves hemodynamics in cardiac tamponade, but classic signs like pulsus paradoxus may be absent in patients with pre-existing elevated pulmonary arterial wedge pressure, such as those with chronic renal failure.

Cite This Study

Reddy et al. (1978) studied this question.

synapsesocial.com/papers/69d56b4175589c71d767c9bb https://doi.org/10.1161/01.cir.58.2.265

View Full Paper

Ask AI

Bookmark

Cardiac tamponade: hemodynamic observations in man.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Cardiac tamponade: hemodynamic observations in man.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider