Does cryoballoon ablation with the second-generation device prevent acute pulmonary vein reconnection in patients undergoing pulmonary vein isolation?
Second-generation cryoballoon ablation has a very low rate of acute PV reconnection, and specific temperature and rewarming parameters can predict durable isolation, potentially eliminating the need for adenosine testing.
The incidence of spontaneous and adenosine-induced PV reconnection following ablation with the novel CB-Adv is very low occurring in 4% of initially isolated veins. Nadir temperature 28 seconds identified absence of acute reconnections, thus avoiding prolonged waiting time and adenosine challenge in such cases.
Ciconte et al. (Fri,) studied this question.