Does pulmonary artery denervation improve hemodynamics and right ventricular dysfunction in dogs with pulmonary arterial hypertension?
Pulmonary artery denervation improves hemodynamics and right ventricular dysfunction in a canine model of pulmonary arterial hypertension, potentially via local RAAS downregulation.
PADN improves hemodynamics and relieves RV dysfunction in dogs with PAH, which can be associated with the downregulating RAAS activity in local tissue.
Liu et al. (Mon,) studied this question.