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February 23, 2016SHILAP Revista de lepidopterología243 citationsOpen Access

Cardiovascular Event Prediction and Risk Reclassification by Coronary, Aortic, and Valvular Calcification in the Framingham Heart Study

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UHUdo HoffmannJMJoseph M. MassaroRDRalph B. D’Agostino

Structured PICO

Does assessment of coronary, aortic, and valvular calcification improve risk prediction for major coronary heart disease and CVD beyond standard risk factors in asymptomatic community-dwelling persons?

P
Population
Asymptomatic community-dwelling persons from the Framingham Heart Study
I
Intervention
Assessment of coronary, aortic, and valvular calcification (CAC)
C
Comparator
Standard cardiovascular risk factors
O
Outcome
Major coronary heart disease and cardiovascular disease (CVD) events (assessed via discrimination and risk reclassification)hard clinical

Coronary artery calcification scoring provides significant clinical value beyond traditional risk factors by accurately reclassifying the majority of intermediate-risk asymptomatic patients.

Abstract

CAC improves discrimination and risk reclassification for major coronary heart disease and CVD beyond risk factors in asymptomatic community-dwelling persons and accurately reclassifies two-thirds of the intermediate-risk population.

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Cite This Study

Hoffmann et al. (2016) studied this question.

synapsesocial.com/papers/69d56c2275589c71d767cbffhttps://doi.org/10.1161/jaha.115.003144
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