August 25, 2023Open Access

Non-vitamin K Antagonist Oral Anticoagulant, Warfarin, and ABC Pathway Adherence on Hierarchical Outcomes: Win Ratio Analysis of the COOL-AF Registry

Structured PICO

Do NOACs and ABC pathway adherence improve hierarchical composite outcomes compared to warfarin and nonadherence in patients with atrial fibrillation?

Population

Patients with atrial fibrillation (AF) from the COOL-AF Registry

Intervention

Non-vitamin K Antagonist Oral Anticoagulants (NOACs) and ABC pathway adherence

Comparator

Warfarin and ABC pathway nonadherence

Outcome

Hierarchical composite outcomecomposite

In patients with atrial fibrillation, the use of NOACs and adherence to the ABC pathway significantly improve hierarchical composite outcomes compared to warfarin and nonadherence.

Abstract

This Win Ratio analysis demonstrates the significant benefits of NOACs over warfarin and ABC pathway adherence over nonadherence in reducing the composite outcome in patients with AF.

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