Why the study?
What is the prevalence and predominant phenotype of left-ventricular hypertrophy in the obese population?
What is the prevalence and predominant phenotype of left-ventricular hypertrophy in the obese population?
Obesity is associated with a consistent presence of LVH, predominantly eccentric, highlighting the importance of obesity management to prevent incident heart failure.
Supports obesity-LVH screening consideration; leaves open whether eccentric phenotype warrants phenotype-specific HF prevention trials.
Our analysis shows that LVH is present in a consistent fraction of the obese population and that eccentric hypertrophy prevails over the concentric phenotype. As obesity-related LVH is a powerful risk factor for systolic/diastolic dysfunction, the prevention/treatment of obesity may have a strong, favourable impact on incident heart failure.
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Cuspidi et al. (2013) studied this question.
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