Why the study?
Does Whole-Lung Irradiation (WLI) improve survival in patients with Ewing Sarcoma Family Tumors and Pulmonary Metastases?
Does Whole-Lung Irradiation (WLI) improve survival in patients with Ewing Sarcoma Family Tumors and Pulmonary Metastases?
Whole-lung irradiation may provide survival benefits for patients with Ewing sarcoma and pulmonary metastases who have a poor response to induction chemotherapy.
May support WLI consideration in poor responders; hypothesis-generating and requires prospective validation.
The comparable survival of patients with poor and good response of PM to induction chemotherapy suggests that WLI may benefit poor responders. The use of WLI in good responders may provide similar benefit and merits further study.
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Spunt et al. (2001) studied this question.
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