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January 1, 2012SHILAP Revista de lepidopterologíaOpen Access

The Relationship between Heart Rate Variability and Adiposity Differs for Central and Overall Adiposity

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Why the study?

Is central adiposity (waist circumference) more strongly associated with reduced heart rate variability than overall adiposity (BMI)?

Population

159 participants (aged 29-96 years) from a subset of the Baltimore Longitudinal Study of Aging

Comparison

Waist circumference as a measure of central… vs Body mass index as a measure of overall adiposity

Design

Cross-sectional

Authors

BWB. Gwen WindhamPreventive CardiologySFStefano FumagalliUniversity of Modena and Reggio EmiliaABAlessandro BlèNational Institutes of Health

Discussion

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Implication

Central adiposity may relate to lower HRV in younger adults; hypothesis-generating and leaves open causal or interventional implications.

Structured PICO

Is central adiposity (waist circumference) more strongly associated with reduced heart rate variability than overall adiposity (BMI)?

P
Population
159 participants (aged 29-96 years) from a subset of the Baltimore Longitudinal Study of Aging
I
Intervention
Waist circumference (WC) as a measure of central adiposity
C
Comparator
Body mass index (BMI) as a measure of overall adiposity
O
Outcome
Time domain heart rate variability (HRV) variables SDNN (standard deviation of successive differences in normal-to-normal intervals) and RMSSD (root mean square of successive differences in normal-to-normal intervals) calculated from 24-hour Holter recordingssurrogate

Central adiposity (waist circumference), rather than overall adiposity (BMI), is associated with declines in autonomic nervous system function as measured by heart rate variability in younger adults.

Cite This Study

Windham et al. (2012) studied this question.

synapsesocial.com/papers/69d56ddb75589c71d767d13ehttps://doi.org/10.1155/2012/149516
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Relation of Body Fat Distribution to Ischemic Heart Disease1995 · 115 citations
  2. 2Determinants of Short-Period Heart Rate Variability in the General Population2001 · 87 citations
  3. 3Association of hyperglycemia with reduced heart rate variability (The Framingham Heart Study)2000 · 440 citations
  4. 4Dysregulation of the Autonomic Nervous System Can Be a Link between Visceral Adiposity and Insulin Resistance2005 · 113 citations
  5. 5Circadian Profile of Cardiac Autonomic Nervous Modulation in Healthy Subjects:2003 · 534 citations