Aortic stenosis is primarily a degenerative-calcific disease with multiple potential risk factors requiring further confirmation.
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Reinforces degenerative-calcific etiology as dominant in aortic stenosis; leaves open confirmation of modifiable risk factors for prevention.
The abnormalities of aortic valve morphology and function represent the most common cardiac-valve lesion particularly in elderly. The etiology of aortic stenosis is degenerative-calcific in the majority of patients. Many risk factors seems to be linked to the calcification and the stenosis of the aortic valve but they must be confirmed. In this review the etiology and the possible physiopathology of the aortic valve stenosis is discussed.
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Faggiano et al. (2006) studied this question.
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