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April 28, 2009Diabetes642 citationsOpen Access

The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes

PGPer‐Henrik GroopMTMerlin C. ThomasJMJohn L. Moran

Key Points

  • To evaluate the relationship between the presence and severity of chronic kidney disease and all-cause mortality in individuals with type 1 diabetes.
  • Evaluated mortality risk in a large, contemporary cohort of individuals with type 1 diabetes.
  • Assessed independent associations across different stages of kidney disease severity.
  • Observed a statistically independent, graded association where increasing severity of chronic kidney disease corresponded to higher all-cause mortality risk.
  • Identified chronic kidney disease prevention and management as critical factors for improving survival outcomes in type 1 diabetes.

Abstract

An independent graded association was observed between the presence and severity of kidney disease and mortality in a large contemporary cohort of individuals with type 1 diabetes. These findings highlight the clinical and public health importance of chronic kidney disease and its prevention in the management of type 1 diabetes.

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Cite This Study

Groop et al. (2009) studied this question.

synapsesocial.com/papers/69d56e0f75589c71d767d341https://doi.org/10.2337/db08-1543
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