Why the study?
Does multiple arterial grafting reduce the composite of death, stroke, myocardial infarction, or repeat revascularization compared to single arterial grafting in patients younger than 70 years with left main and/or multivessel disease?
Does multiple arterial grafting reduce the composite of death, stroke, myocardial infarction, or repeat revascularization compared to single arterial grafting in patients younger than 70 years with left main and/or multivessel disease?
The ROMA trial protocol outlines a large-scale randomized comparison to determine if multiple arterial grafts offer superior clinical outcomes over a single arterial graft in patients under 70 undergoing coronary artery bypass grafting.
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Enables definitive RCT of multiple vs single arterial grafting; extends low-certainty observational evidence in younger CABG patients.
Gaudino et al. (2017) studied this question.
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