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Acknowledging the dynamic and evolving nature of less-invasive aortic valve therapies, further refinements of clinical research processes are required. The adoption of these updated and newly proposed VARC-3 endpoints and definitions will ensure homogenous event reporting, accurate adjudication, and appropriate comparisons of clinical research studies involving devices and new therapeutic strategies.
“The establishment of the VARC-3 definition in 2021 enabled consistent reporting of durability outcomes and more meaningful comparisons between TAVI and SAVR.”
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Philippe Généreux
Nicolò Piazza
Maria Alu
Journal of the American College of Cardiology
Columbia University
University of British Columbia
Icahn School of Medicine at Mount Sinai
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Généreux et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69d56e3075589c71d767d4b9 — DOI: https://doi.org/10.1016/j.jacc.2021.02.038