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Design
Guideline
The VARC-2 consensus document provides updated standardized clinical endpoint definitions for transcatheter aortic valve implantation trials.
The aim of the current Valve Academic Research Consortium (VARC)-2 initiative was to revisit the selection and definitions of transcatheter aortic valve implantation (TAVI) clinical endpoints to make them more suitable to the present and future needs of clinical trials. In addition, this document is intended to expand the understanding of patient risk stratification and case selection.
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Kappetein et al. (2012) studied this question.
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