Population
Skeletal muscle models (striated muscle)
Design
Preclinical
Authors
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Disruption of MG53-dysferlin-Cav3 impairs repair; hypothesis-generating for targeted therapies in Cav3-related muscular and cardiovascular disease.
A molecular complex of MG53, dysferlin, and Cav3 is essential for muscle membrane repair, and its disruption by Cav3 mutations causes defective repair, offering a potential therapeutic target for muscular and cardiovascular diseases.
Cai et al. (2009) studied this question.
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