Why the study?
Does gender influence left ventricular remodeling patterns in obese individuals without traditional cardiovascular risk factors?
Does gender influence left ventricular remodeling patterns in obese individuals without traditional cardiovascular risk factors?
Gender-specific differences in left ventricular remodeling (predominantly concentric in men vs. mixed in women) may explain the higher cardiovascular mortality observed in obese men.
May support sex-specific LV assessment in obesity; leaves open links to mortality and need for prospective data.
In the absence of traditional cardiovascular risk factors, obese men show predominantly concentric hypertrophy, whereas obese women exhibit both eccentric and concentric hypertrophy. As concentric hypertrophy is more strongly related to cardiovascular mortality than eccentric hypertrophy, our observations may explain the observed gender difference in obesity-related mortality.
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Rider et al. (2012) studied this question.
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