Does gender influence left ventricular remodeling patterns in obese individuals without traditional cardiovascular risk factors?
Gender-specific differences in left ventricular remodeling (predominantly concentric in men vs. mixed in women) may explain the higher cardiovascular mortality observed in obese men.
In the absence of traditional cardiovascular risk factors, obese men show predominantly concentric hypertrophy, whereas obese women exhibit both eccentric and concentric hypertrophy. As concentric hypertrophy is more strongly related to cardiovascular mortality than eccentric hypertrophy, our observations may explain the observed gender difference in obesity-related mortality.
Rider et al. (Wed,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: