Why the study?
Cardiovascular diseases are highly prevalent worldwide, prompting an analysis of prescribing trends and treatment appropriateness regarding adherence to guidelines, essential medicine use, and generic drug prescriptions.
This study reveals significant polypharmacy (average 13.2 drugs per patient) and low rates of generic and essential drug prescribing in cardiovascular patients, highlighting a need for optimized medication management.
Prescribing patterns should not yet change practice in cardiovascular patients; leaves open the need for prospective studies on optimization.
Cardiovascular diseases (CVDs), encompassing conditions like coronary artery disease, hypertension and ischemic heart disease, are highly prevalent worldwide. This study analyzed prescribing trends and treatment appropriateness in CVD patients, focusing on adherence to guidelines, essential medicine use and generic drug prescriptions. A cross-sectional observational study was conducted on CVD-diagnosed patients. Data on prescribed medications-including drug classes, generic prescriptions and adherence to the Essential Drug List (EDL)-were collected and analyzed using IBM SPSS version 26.0. The most frequently prescribed drug classes included antiplatelets, diuretics and hypolipidemics. Aspirin was the most commonly prescribed medication (58.1%), followed by furosemide (36.5%), amlodipine (32.4%) and rosuvastatin (24.3%). Statins and calcium channel blockers were prescribed more often than angiotensin II receptor blockers and beta-blockers. On average, 13.2 drugs were prescribed per patient, with only 28.8% prescribed generically. Furthermore, 47.3% of medications were on the EDL. This study highlights the high prevalence of CVDs and the common drug classes prescribed to manage them. These findings provide important insights into current prescribing trends, particularly the frequent use of anti-hypertensive, antiplatelets, diuretics and hypolipidemics and suggest areas for optimizing medication management in this population. Additionally, there is a need to better manage polypharmacy in CVD patients.
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Chikatipalli et al. (2024) studied this question.
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