Why the study?
Does exercise stress echocardiography reveal subclinical left ventricular dysfunction in patients with obstructive sleep apnea and preserved LVEF?
Does exercise stress echocardiography reveal subclinical left ventricular dysfunction in patients with obstructive sleep apnea and preserved LVEF?
Patients with obstructive sleep apnea and preserved LVEF exhibit subclinical systolic and diastolic dysfunction detectable by exercise stress echocardiography.
Exercise stress echo may unmask subclinical LV dysfunction in OSA with preserved LVEF; hypothesis-generating and requires prospective validation before practice change.
Evaluation of diastolic function and myocardial deformation during exercise is feasible through stress echocardiography. OSA patients with preserved LVEF show subclinical LV systolic dysfunction, impaired LV systolic and diastolic reserve, reduced exercise tolerance, and increased peripheral levels of OB. Therapy aimed at increasing LV diastolic function reserve might improve the quality of life and exercise tolerability in OSA patients.
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D’Andrea et al. (2020) studied this question.
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