Why the study?
Do clinical presentation and outcomes differ between men and women with acute coronary syndromes?
Do clinical presentation and outcomes differ between men and women with acute coronary syndromes?
Sex differences exist in the presentation and outcomes of acute coronary syndromes, potentially reflecting underlying pathophysiologic and anatomical differences.
Sex differences in ACS persist beyond baseline factors; hypothesis-generating for mechanisms but should not yet change practice.
Women and men with acute coronary syndromes had different clinical profiles, presentation, and outcomes. These differences could not be entirely accounted for by differences in base-line characteristics and may reflect pathophysiologic and anatomical differences between men and women.
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Hochman et al. (1999) studied this question.