Why the study?
Do negative results of atherosclerosis-imaging tests, particularly a coronary artery calcium score of 0, reduce estimated CVD risk in individuals assessed for cardiovascular disease?
Do negative results of atherosclerosis-imaging tests, particularly a coronary artery calcium score of 0, reduce estimated CVD risk in individuals assessed for cardiovascular disease?
A coronary artery calcium score of 0 provides the greatest downward shift in estimated CVD risk, helping identify patients who may not benefit from lifelong preventive pharmacotherapy.
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Negative CAC may refine risk estimates downward; leaves open effects on therapy and outcomes without RCTs.
Blaha et al. (2016) studied this question.