Why the study?
Do negative results of atherosclerosis-imaging tests, particularly a coronary artery calcium score of 0, reduce estimated CVD risk in individuals assessed for cardiovascular disease?
Do negative results of atherosclerosis-imaging tests, particularly a coronary artery calcium score of 0, reduce estimated CVD risk in individuals assessed for cardiovascular disease?
A coronary artery calcium score of 0 provides the greatest downward shift in estimated CVD risk, helping identify patients who may not benefit from lifelong preventive pharmacotherapy.
Negative CAC may refine risk estimates downward; leaves open effects on therapy and outcomes without RCTs.
Negative results of atherosclerosis-imaging tests, particularly coronary artery calcium score of 0, resulted in the greatest downward shift in estimated CVD risk. These results may help guide discussions on the identification of individuals less likely to receive net benefit from lifelong preventive pharmacotherapy.
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Blaha et al. (2016) studied this question.
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