Why the study?
Does fatiguing inspiratory muscle work reduce resting leg blood flow and increase limb vascular resistance in healthy humans?
Population
6 healthy human subjects at rest
Comparison
Fatiguing inspiratory work to the point of task… vs Increased central inspiratory motor output…
Design
Other
Authors
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May influence limb perfusion during respiratory stress in health; leaves open relevance to exercise intolerance or disease states.
Does fatiguing inspiratory muscle work reduce resting leg blood flow and increase limb vascular resistance in healthy humans?
Fatiguing inspiratory muscle work elicits a metaboreflex originating in the diaphragm that causes a reflex reduction in resting leg blood flow and an increase in limb vascular resistance.
Sheel et al. (2001) studied this question.
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