Why the study?
Does fatiguing inspiratory muscle work reduce resting leg blood flow and increase limb vascular resistance in healthy humans?
Does fatiguing inspiratory muscle work reduce resting leg blood flow and increase limb vascular resistance in healthy humans?
Fatiguing inspiratory muscle work elicits a metaboreflex originating in the diaphragm that causes a reflex reduction in resting leg blood flow and an increase in limb vascular resistance.
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May influence limb perfusion during respiratory stress in health; leaves open relevance to exercise intolerance or disease states.
Sheel et al. (2001) studied this question.
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