What question did this study set out to answer?

Summarize scalable fabrication technologies, structural classifications, and regulatory requirements governing the translation of liposomal drug formulations.

February 22, 2013Nanoscale Research LettersOpen Access

Liposome: classification, preparation, and applications

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Authors

AAAbolfazl AkbarzadehIran University of Medical Sciences RRRogaie Rezaei-SadabadyUniversity of Tabriz SDSoodabeh DavaranYeditepe University

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Implication

Review demonstrates scalable fabrication and targeted delivery of liposome platforms in therapeutic applications, highlighting industrial feasibility and regulatory compliance.

Key Points

Summarize scalable fabrication technologies, structural classifications, and regulatory requirements governing the translation of liposomal drug formulations.
Evaluated scalable preparation methods suitable for industrial-scale manufacturing of liposomal carriers.
Analyzed structural modifications affecting circulation longevity, including adjustments to vesicle size, lipid composition, surface charge, and glycolipid conjugation.
Reviewed industrial translation criteria and regulatory frameworks established in FDA and EMEA guidance documents.
Second-generation liposomes achieve extended systemic circulation through tailored lipid membrane compositions, charge adjustments, and defined vesicle sizing.
Surface engineering utilizing molecules such as glycolipids and sialic acid facilitates targeted active molecule delivery across multidisciplinary clinical settings.
Translation to commercial use depends on balancing scalable fabrication techniques against technical limitations and formal regulatory standards.

Cite This Study

Akbarzadeh et al. (2013) studied this question.

synapsesocial.com/papers/69d56fb275589c71d767dab2 https://doi.org/10.1186/1556-276x-8-102

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Implication

Review demonstrates scalable fabrication and targeted delivery of liposome platforms in therapeutic applications, highlighting industrial feasibility and regulatory compliance.

Liposome: classification, preparation, and applications

Discussion

Member takes

Implication

Key Points

Cite This Study

Liposome: classification, preparation, and applications

Discussion

Member takes

Implication

Key Points

Cite This Study

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