Why the study?
Does early perioperative exposure to a statin reduce all-cause perioperative mortality and complications in patients undergoing major noncardiac surgery?
Does early perioperative exposure to a statin reduce all-cause perioperative mortality and complications in patients undergoing major noncardiac surgery?
Perioperative statin use is associated with reduced mortality and complications after major noncardiac surgery, though observational biases limit definitive conclusions.
Supports perioperative statin hypothesis in noncardiac surgery; hypothesis-generating and should not yet change practice.
Early perioperative exposure to a statin was associated with a significant reduction in all-cause perioperative mortality and several cardiovascular and noncardiovascular complications. However, the potential for selection biases in these results must be considered.
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London et al. (2016) studied this question.
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