Why the study?
What are the rates, sites, and procedural predictors of late pulmonary vein reconnection following cryoballoon ablation?
What are the rates, sites, and procedural predictors of late pulmonary vein reconnection following cryoballoon ablation?
Late pulmonary vein reconnection after cryoballoon ablation is relatively low, and durable isolation can be predicted by specific intraprocedural parameters such as faster time to isolation and colder nadir temperatures.
May inform cryoballoon endpoints to reduce reconnection; leaves open prospective validation before practice change.
The rate of late PV reconnection after CB ablation was low (1.18 PVs/patient). The most frequent sites of reconnections were the superior-anterior portions for the upper PVs and the inferior-posterior portions for the lower PVs. Faster time to isolation, colder nadir temperatures and achievement of - 40 °C within 60 s were associated with durable PV isolation.
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Mugnai et al. (2022) studied this question.
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