Why the study?
Do depressive symptoms moderate the influence of hostility on serum Interleukin-6 and C-Reactive Protein in older adults?
Do depressive symptoms moderate the influence of hostility on serum Interleukin-6 and C-Reactive Protein in older adults?
Depressive symptoms moderate the relationship between hostility and inflammation (IL-6, CRP) in older adults, suggesting a synergistic effect on cardiovascular risk.
Depressive symptoms may moderate hostility-inflammation links in older adults; hypothesis-generating and should not yet change practice.
Our findings suggest that depressive symptoms may moderate the hostility-inflammation relationship such that hostility may augment inflammatory processes relevant to coronary artery disease only in the presence of depressive symptoms. Our results also extend previous findings from younger adults to older adults from the general community.
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Stewart et al. (2008) studied this question.
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