Why the study?
Diagnosis of von Willebrand disease can be difficult in young children who have not experienced bleeding challenges, prompting evaluation of the correlation between VWF levels and bleeding during tonsillectomy.
Do low von Willebrand factor (VWF) levels predict surgical and postoperative bleeding in children undergoing tonsillectomy?
Population
1399 children ages 0 to 18 undergoing tonsillectomy without bleeding history
Comparison
Postoperative bleeding vs no postoperative bleeding
Design
Prospective cohort study
Authors
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Low VWF levels were not associated with post-tonsillectomy bleeding in children; leaves open utility of preoperative VWF screening.
Do low von Willebrand factor (VWF) levels predict surgical and postoperative bleeding in children undergoing tonsillectomy?
Low VWF levels in young children undergoing tonsillectomy are relatively common but do not correlate with or predict postoperative bleeding.
Gill et al. (2020) studied this question.
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