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December 12, 2010Journal of Interferon & Cytokine Research

The Oligoadenylate Synthetase Family: An Ancient Protein Family with Multiple Antiviral Activities

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Authors

HKHelle KristiansenOdense University Hospital HGHans Henrik GadAarhus University SESigne Eskildsen-LarsenNovozymes (Denmark)

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Implication

Does not alter clinical antiviral strategies; leaves open RNase L-independent OAS pathways for targeted investigation.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Kristiansen et al. (2010) studied this question.

synapsesocial.com/papers/69d570e675589c71d767dfee https://doi.org/10.1089/jir.2010.0107

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase.1978 · 191 citations
2The 69-kDa 2-5A synthetase is composed of two homologous and adjacent functional domains.1992 · 99 citations
3A Bipartite Model of 2-5A-dependent RNase L1997 · 113 citations
4Positional cloning of the murine flavivirus resistance gene2002 · 269 citations
5Single Nucleotide Polymorphisms in Genes for 2′‐5′‐Oligoadenylate Synthetase and RNase L in Patients Hospitalized with West Nile Virus Infection2005 · 128 citations