Why the study?
Does discontinuation of aspirin 1 to 3 months after PCI with continued P2Y12 inhibitor monotherapy reduce bleeding without increasing MACE in patients after PCI?
Does discontinuation of aspirin 1 to 3 months after PCI with continued P2Y12 inhibitor monotherapy reduce bleeding without increasing MACE in patients after PCI?
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Discontinuing aspirin 1 to 3 months post-PCI while continuing a P2Y12 inhibitor reduces bleeding risk without increasing ischemic events.
Discontinuation of aspirin with continued P2Y₁₂ inhibitor monotherapy reduces risk of bleeding when stopped 1 to 3 months after PCI. An increased risk of MACE was not observed after discontinuation of aspirin, including in patients with acute coronary syndrome.
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O’Donoghue et al. (2020) studied this question.
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