Does extended prophylaxis with aspirin prevent symptomatic venous thromboembolism compared to rivaroxaban in patients who received 5 days of rivaroxaban prophylaxis after total hip or total knee arthroplasty?
Extended prophylaxis with aspirin is not significantly different from rivaroxaban for preventing symptomatic VTE after hip or knee arthroplasty following an initial 5-day course of rivaroxaban.
Among patients who received 5 days of rivaroxaban prophylaxis after total hip or total knee arthroplasty, extended prophylaxis with aspirin was not significantly different from rivaroxaban in the prevention of symptomatic venous thromboembolism. (Funded by the Canadian Institutes of Health Research; ClinicalTrials.gov number, NCT01720108 .).
Anderson et al. (Wed,) studied this question.