Why the study?
Does the updated cTnT-hs assay improve tolerance to biotin interference while maintaining agreement with the previous cTnT-hs assay?
Does the updated cTnT-hs assay improve tolerance to biotin interference while maintaining agreement with the previous cTnT-hs assay?
An updated high-sensitivity troponin T assay maintains clinical concordance with the previous version while potentially reducing biotin interference.
May reduce biotin interference in troponin testing; leaves open larger validation before routine adoption.
The updated cTnT-hs* assay may provide greater tolerance to biotin interference, and shows good analytical and clinical agreement/concordance with the previous cTnT-hs assay.
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Meyer et al. (2020) studied this question.
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