Why the study?
Does the combined assessment of systolic septal longitudinal strain gradient and diastolic deceleration time aid in differentiating cardiac amyloidosis from other causes of concentric left ventricular hypertrophy?
Does the combined assessment of systolic septal longitudinal strain gradient and diastolic deceleration time aid in differentiating cardiac amyloidosis from other causes of concentric left ventricular hypertrophy?
Combining specific systolic strain and diastolic filling echocardiographic parameters provides a useful diagnostic tool to differentiate cardiac amyloidosis from other causes of concentric LVH.
May support noninvasive differentiation of cardiac amyloidosis in concentric LVH; leaves open need for prospective validation before clinical adoption.
A systolic septal longitudinal base-to-apex strain gradient (septal apical to basal LSsys ratio >2.1), combined with a shortened diastolic deceleration time of early filling (deceleration time of early filling <200 milliseconds), aids in differentiating CA from other causes of concentric left ventricular hypertrophy.
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Liu et al. (2013) studied this question.
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