Why the study?
Does amiodarone reduce sudden death or prolong survival in patients with congestive heart failure and asymptomatic ventricular arrhythmia?
Does amiodarone reduce sudden death or prolong survival in patients with congestive heart failure and asymptomatic ventricular arrhythmia?
Amiodarone does not improve survival or reduce sudden death in patients with heart failure and asymptomatic ventricular arrhythmias, despite effectively suppressing arrhythmias and improving ventricular function.
Avoid routine amiodarone use for survival in heart failure with asymptomatic arrhythmias; confirms neutral mortality effect despite arrhythmia suppression.
Although amiodarone was effective in suppressing ventricular arrhythmias and improving ventricular function, it did not reduce the incidence of sudden death or prolong survival among patients with heart failure, except for a trend toward reduced mortality among those with nonischemic cardiomyopathy.
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Singh et al. (1995) studied this question.
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