Pregnancy can unmask severe cardiovascular complications in previously asymptomatic patients with irradiation-induced constrictive pericarditis, leading to adverse maternal and fetal outcomes.
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Alerts clinicians to decompensation risk in asymptomatic constrictive pericarditis during pregnancy; leaves open need for preconception risk stratification data.
A case is reported of a 24-year-old primigravida who had severe effusive constrictive pericarditis secondary to mediastinal irradiation following chemotherapy for Hodgkin's disease. Pregnancy was threatened by serious maternal cardiovascular complications, and a non-viable fetus was born spontaneously and prematurely. Patient was completely asymptomatic before pregnancy.
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Bakri et al. (1992) studied this question.
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