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Reveals elevated small dense LDL cholesterol is an independent risk factor for acute ischemic stroke and poor outcomes, suggesting its utility in risk prediction.
Elevated levels of sdLDL-C were associated with a higher prevalence of AIS, especially in non-cardioembolic stroke subtypes. After adjustment for other risk factors, sdLDL-C was found to be an independent risk factor for AIS. Also, sdLDL-C level was strongly associated with AIS severity and poor functional outcomes. Logistic regression models for AIS risk and prognosis prediction were established to help clinicians provide better prevention for high-risk subjects and monitor their prognosis.
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Zhou et al. (2020) studied this question.
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