Why the study?
Does the GRACE risk score provide superior discrimination compared to the TIMI risk score for predicting mortality in patients with acute coronary syndromes?
Does the GRACE risk score provide superior discrimination compared to the TIMI risk score for predicting mortality in patients with acute coronary syndromes?
The GRACE risk score provides superior prognostic discrimination compared to the TIMI score in UA/NSTEMI patients, highlighting the importance of comprehensive risk factor inclusion over scoring simplicity.
May favor GRACE for UA/NSTEMI stratification; leaves open prospective validation before changing ACS practice.
The GRACE scores provided superior discrimination as compared with the TIMI UA/NSTEMI score in predicting in-hospital and 6-month mortality in UA/NSTEMI patients, although the GRACE and TIMI STEMI scores performed equally well in STEMI patients. The observed discriminative deficit of the TIMI UA/NSTEMI score likely results from the omission of key risk factors rather than from the relative simplicity of the scoring system.
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Aragam et al. (2009) studied this question.
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