What question did this study set out to answer?

To assess the clinical value and optimal monitoring frequency of serial blood lactate measurements (lactate kinetics) in predicting outcomes among critically ill patients.

August 12, 2016Critical CareOpen Access

The value of blood lactate kinetics in critically ill patients: a systematic review

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To assess the clinical value and optimal monitoring frequency of serial blood lactate measurements (lactate kinetics) in predicting outcomes among critically ill patients.
Systematic review of published clinical studies evaluating dynamic changes in blood lactate levels across diverse intensive care and acute illness populations, including septic and nonseptic cohorts.
Decreasing blood lactate concentrations consistently correlate with improved patient outcomes across varied clinical settings, with prognostic validity remaining independent of baseline initial lactate values.
Lactate changes occur relatively slowly in critically ill populations, indicating that repeat sampling intervals of every 1 to 2 hours are clinically sufficient for monitoring acute response.

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Implication

Systematic review demonstrates that decreasing blood lactate levels correlate with improved clinical outcomes in critically ill patients, indicating the prognostic utility of serial testing.

Cite This Study

Vincent et al. (2016) studied this question.

synapsesocial.com/papers/69d572ce75589c71d767e7dc https://doi.org/10.1186/s13054-016-1403-5

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Implication

Systematic review demonstrates that decreasing blood lactate levels correlate with improved clinical outcomes in critically ill patients, indicating the prognostic utility of serial testing.

The value of blood lactate kinetics in critically ill patients: a systematic review

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Discussion

Implication

Cite This Study

The value of blood lactate kinetics in critically ill patients: a systematic review

Key Points

Discussion

Implication

Cite This Study

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