Large arterial stiffening and carotid remodeling begin at the very early stages of chronic kidney disease.
Early arterial stiffening in mild CKD may prompt earlier screening; this observational finding leaves open causal and therapeutic implications.
The large arterial stiffening starts early during CKD, even in participants with a very mild reduction in renal function.
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Zanoli et al. (2019) studied this question.
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