Evolving Indications of Transcatheter Aortic Valve Replacement—Where Are We Now, and Where Are We Going

Jules Mesnier; Vassili Panagides; Jorge Nuche; Josep Rodés‐Cabau

doi:10.3390/jcm11113090

May 30, 2022Journal of Clinical MedicineOpen Access

Evolving Indications of Transcatheter Aortic Valve Replacement—Where Are We Now, and Where Are We Going

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Why the study?

Indications for TAVR have steadily expanded over the last decade since early trials in inoperable or very high risk patients, establishing it as the most common treatment for aortic valve stenosis in elderly patients.

Key Points

To review the evolving clinical indications of transcatheter aortic valve replacement (TAVR) and explore emerging areas for future clinical expansion.
Reviewed historical trial data and clinical transitions of TAVR from high-risk populations to routine clinical practice.
Assessed comparative outcomes between TAVR and surgical aortic valve replacement (SAVR) across evolving risk categories.
TAVR has advanced from an intervention restricted to inoperable or very high-risk patients to the leading treatment modality for aortic valve stenosis in elderly populations over surgical replacement.
Ongoing clinical investigations continue to broaden the scope of TAVR toward lower-risk profiles and expanded anatomical indications.

Structured PICO

P

Population

Patients with aortic valve stenosis, including elderly, inoperable, or very high-risk patients

I

Intervention

Transcatheter aortic valve replacement (TAVR)

C

Comparator

Surgical aortic valve replacement (SAVR)

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Implication

This review summarizes the current and expanding indications for transcatheter aortic valve replacement, which has become the most common treatment for aortic stenosis in elderly patients.

Abstract

Indications for transcatheter aortic valve replacement (TAVR) have steadily increased over the last decade since the first trials including inoperable or very high risk patients. Thus, TAVR is now the most common treatment of aortic valve stenosis in elderly patients (vs. surgical aortic valve replacement -SAVR-). In this review, we summarize the current indications of TAVR and explore future directions in which TAVR indications can expand.

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Cite This Study

Mesnier et al. (2022) studied this question.

synapsesocial.com/papers/69d57320994d36ef590c9ec1 https://doi.org/10.3390/jcm11113090

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Evolving Indications of Transcatheter Aortic Valve Replacement—Where Are We Now, and Where Are We Going

Figures

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Evolving Indications of Transcatheter Aortic Valve Replacement—Where Are We Now, and Where Are We Going

Figures

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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