Indexing left ventricular mass to fat-free mass rather than traditional body size metrics may improve the sensitivity of detecting left ventricular hypertrophy.
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May improve LVH detection via fat-free mass indexing; hypothesis-generating and requires prospective validation before practice change.
LV mass is more strongly related to FFM than to adipose mass, waist/hip ratio, body mass index, or height-based surrogates for lean body weight; LV mass/FFM criteria may increase sensitivity to detect LV hypertrophy.
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Bella et al. (1998) studied this question.
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