December 12, 2018Hypertension

Lifetime risk of stroke death at index age 35 years was 14.6% for men and 14.3% for women with grade 3 hypertension, compared to 6.1% and 4.8% for optimal blood pressure, with CHD death risks showing similar but lower elevations (≤7.2%).

View Full Paper

Ask AI

Bookmark

Why the study?

Few studies have focused on the lifetime risks of stroke and coronary heart disease categorized by fine blood pressure levels in Asian populations.

Does higher blood pressure increase the lifetime risk of stroke and CHD death in a Japanese population?

Population

107 737 Japanese from 13 cohorts

Comparison

Blood pressure levels categorized as optimal, normal, high-normal, and grades 1-3 hypertension

Design

Individual participant data meta-analysis

Follow-up

Mean 15.2±5.3 years

Authors

MSMichihiro Satoh TOTakayoshi Ohkubo KAKei Asayama

Discussion

Member takes

Overview

Supports early BP control to curb stroke mortality; confirms graded lifetime risks in Japanese adults.

Structured PICO

Does higher blood pressure increase the lifetime risk of stroke and CHD death in a Japanese population?

Population

107,737 Japanese adults from 13 cohorts, mean age 55.1 years, 42.4% men.

Intervention

Blood pressure categories (optimal, normal, high-normal, grade 1, grade 2, grade 3 hypertension)

Comparator

Optimal blood pressure

Outcome

Lifetime risk of stroke death and coronary heart disease (CHD) deathhard clinical

Higher blood pressure categories are associated with a significantly increased lifetime risk of stroke and CHD death in the Japanese population, with stroke death risk being roughly double that of CHD death.

Cite This Study

Satoh et al. (2018) studied this question.

synapsesocial.com/papers/69d5757123f4decff7b4cd36 https://doi.org/10.1161/hypertensionaha.118.11635

View Full Paper

Ask AI

Bookmark

December 12, 2018Hypertension

Lifetime risk of stroke death at index age 35 years was 14.6% for men and 14.3% for women with grade 3 hypertension, compared to 6.1% and 4.8% for optimal blood pressure, with CHD death risks showing similar but lower elevations (≤7.2%).

View Full Paper

Ask AI

Bookmark

Why the study?

Few studies have focused on the lifetime risks of stroke and coronary heart disease categorized by fine blood pressure levels in Asian populations.

Does higher blood pressure increase the lifetime risk of stroke and CHD death in a Japanese population?

Population

107 737 Japanese from 13 cohorts

Comparison

Blood pressure levels categorized as optimal, normal, high-normal, and grades 1-3 hypertension

Design

Individual participant data meta-analysis

Follow-up

Mean 15.2±5.3 years

Authors

MSMichihiro Satoh TOTakayoshi Ohkubo KAKei Asayama

Discussion

Member takes

Overview

Supports early BP control to curb stroke mortality; confirms graded lifetime risks in Japanese adults.

Structured PICO

Does higher blood pressure increase the lifetime risk of stroke and CHD death in a Japanese population?

Population

107,737 Japanese adults from 13 cohorts, mean age 55.1 years, 42.4% men.

Intervention

Blood pressure categories (optimal, normal, high-normal, grade 1, grade 2, grade 3 hypertension)

Comparator

Optimal blood pressure

Outcome

Lifetime risk of stroke death and coronary heart disease (CHD) deathhard clinical

Cite This Study

Satoh et al. (2018) studied this question.

synapsesocial.com/papers/69d5757123f4decff7b4cd36 https://doi.org/10.1161/hypertensionaha.118.11635

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark