Key result
Supine hypertension linked to ~60% higher risk of incident coronary heart disease.
Why the study?
Does supine hypertension increase the risk of incident cardiovascular disease and mortality in middle-aged adults without known cardiovascular disease?
Comparison
Supine hypertension vs seated hypertension alone
Authors
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May flag higher CVD risk missed by seated BP alone; leaves open whether it is an independent modifiable target.
Cohort (n=11,369)
Yes
Does supine hypertension increase the risk of incident cardiovascular disease and mortality in middle-aged adults without known cardiovascular disease?
Hazard Ratio: 1.6 (95% CI 1.45–1.76)
Supine hypertension is a significant independent risk factor for incident cardiovascular disease and mortality, carrying a higher risk than seated hypertension alone.
Giao et al. (2025) conducted a cohort in Cardiovascular disease (n=11,369). Supine hypertension vs. No supine hypertension was evaluated on Incident coronary heart disease (HR 1.60, 95% CI 1.45-1.76). Supine hypertension was associated with an increased risk of incident coronary heart disease (HR 1.60; 95% CI 1.45-1.76), heart failure, stroke, and mortality.
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