Why the study?
The study aimed to investigate the predictive role of the systemic immune inflammation index on AF recurrence following cryoballoon-based AF ablation.
Does a high systemic immune inflammation index (SII) predict atrial fibrillation recurrence in patients undergoing cryoballoon-based ablation?
Does a high systemic immune inflammation index (SII) predict atrial fibrillation recurrence in patients undergoing cryoballoon-based ablation?
A higher Systemic Immune Inflammation Index (SII > 532) is an independent predictor of atrial fibrillation recurrence following cryoballoon ablation, offering a potential prognostic biomarker.
High SII may flag higher AF recurrence risk after cryoballoon ablation; hypothesis-generating and should not yet change practice.
Background: We aimed to investigate the predictive role of systemic immune inflammation index (SII) on atrial fibrillation (AF) recurrence following cryoballoon-based AF ablation. Materials & methods: A total of 370 consecutive patients with symptomatic AF who underwent cryoablation were enrolled. The patients were divided into two groups according to recurrence development. Results: During the follow-up period of 25.0 ± 6.7 months, recurrence was observed in 77 patients (20.8%). Receiver operating characteristic analysis demonstrated that using a cutoff level of 532, SII had a sensitivity of 71% and specificity of 68%. In the multivariate Cox model, high SII was a significant predictor of the recurrence. Conclusion: This study showed that higher SII level is an independent predictor of AF recurrence.
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Kaplan et al. (2023) studied this question.
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